PHR1875

Valsartan Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: D-Valsartan, N-VALERYL-N-{[2’-(1HTETRAZOLE-5-YL)-BIPHENYL-4-YL]-METHYL}-D-VALINE(ent-Valsartan), (R)-N-Valeryl-N-([2′-(1H-tetrazole-5-yl)-biphenyl-4-yl]methyl)valine, N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-D-valine
• 実験式（ヒル表記法）: C₂₄H₂₉N₅O₃
• 分子量: 435.52
• MDL番号: MFCD18252868
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to USP 1708773
• APIファミリー: valsartan
• CofA: current certificate can be downloaded
• 包装: pkg of 30 mg
• アプリケーション: pharmaceutical small molecule
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: CCCCC(=O)N(Cc1ccc(cc1)-c2ccccc2-c3nnn[nH]3)[C@H](C(C)C)C(O)=O
• InChI: 1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1
• InChI Key: ACWBQPMHZXGDFX-JOCHJYFZSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Valsartan Related Compound A is an impurity of valsartan, an orally active specific angiotensin II receptor blocker or angiotensin-II antagonist, which is widely used in treating hypertension by lowering the blood pressure.

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Valsartan may be used as a pharmaceutical reference standard for the determination of the analyte in tablet formulations, bulk and pharmaceutical dosage forms using reversed-phase high-performance liquid chromatography technique.

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAB1041 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS08,GHS07
• シグナルワード: Warning
• 危険有害性情報: H336,H361d
• 注意書き: P202 - P261 - P271 - P280 - P304 + P340 + P312 - P308 + P313
• 危険有害性の分類: Repr. 2 - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable