PHR1494

ピロカルピン 硝酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: Pilocarpine nitrate salt
• 実験式（ヒル表記法）: C₁₁H₁₆N₂O₂ · HNO₃
• CAS番号: 148-72-1
• 分子量: 271.27
• Beilstein: 4171406
• EC Number: 205-723-7
• MDL番号: MFCD00078497
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823416
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 503; traceable to Ph. Eur. P1700000; traceable to USP 1539009
• APIファミリー: pilocarpine
• CofA: current certificate can be downloaded
• 包装: pkg of 500 mg
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
• InChI: 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
• InChI Key: PRZXEPJJHQYOGF-GNAZCLTHSA-N
• 遺伝子情報: human ... CHRM1(1128) , CHRM3(1131)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents.

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

非選択的なムスカリン性アセチルコリン受容体アゴニストで、てんかんの実験的モデル作製に用いられます。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS03,GHS06
• シグナルワード: Danger
• 危険有害性情報: H272,H302,H330
• 注意書き: P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
• 危険有害性の分類: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
• 保管分類コード: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable