92986

N-Propionylglycine

analytical standard

• 別名: 2-(Propionylamino)acetic acid, N-(1-Oxopropyl)glycine, NSC 158539, Propionyl glycine
• 実験式（ヒル表記法）: C₅H₉NO₃
• CAS番号: 21709-90-0
• 分子量: 131.13
• Beilstein: 1759032
• MDL番号: MFCD09049674
• UNSPSCコード: 12352209
• NACRES: NA.24

特性

• グレード: analytical standard
• 品質水準: 100
• アッセイ: ≥98.0% (HPLC)
• シェルフライフ: limited shelf life, expiry date on the label
• アプリケーション: clinical testing
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: OC(CNC(CC)=O)=O
• InChI: 1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)
• InChI Key: WOMAZEJKVZLLFE-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase.

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安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3