91204

無水酢酸

for GC derivatization, LiChropur^™, ≥99.0%

• 化学式: (CH₃CO)₂O
• CAS番号: 108-24-7
• 分子量: 102.09
• Beilstein: 385737
• EC Number: 203-564-8
• MDL番号: MFCD00008705
• UNSPSCコード: 12000000
• PubChem Substance ID: 329770002
• NACRES: NA.22

特性

• グレード: for GC derivatization
• 品質水準: 100
• 蒸気密度: 3.5 (vs air)
• 蒸気圧: 10 mmHg ( 36 °C); 4 mmHg ( 20 °C)
• アッセイ: ≥99.0% (GC); ≥99.0%
• 形状: liquid
• 自己発火温度: 629 °F
• 品質: LiChropur^™
• expl. lim.: 10.3 %
• 反応適合性: reagent type: derivatization reagent; reaction type: Acylations
• テクニック: gas chromatography (GC): suitable
• 蒸発残留物質: ≤0.003%
• 屈折率: n20/D 1.390 (lit.)
• bp: 138-140 °C (lit.)
• mp: −73 °C (lit.)
• 溶解性: H₂O: slightly soluble
• 密度: 1.08 g/mL (lit.)
• SMILES記法: CC(=O)OC(C)=O
• InChI: 1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
• InChI Key: WFDIJRYMOXRFFG-UHFFFAOYSA-N

詳細

詳細

Acetic anhydride is an esterification agent which is corrosive to metals. It is a colourless liquid with strong vinegar-like odour. It is mostly used in making plastics, fibers, pharmaceuticals, dyes and explosives.

Acylation, an alternative to silylation, enables the conversion of compounds that comprise of active hydrogens (-OH, -SH and -NH) into esters, thioesters, and amides by the action of a carboxylic acid or derivative. The carbonyl group adjacent to the halogenated carbons favors the improvement of electron capture detector (ECD) response. Acylation has several benefits:

• It increases the stability of compounds by protecting unstable groups.
• It may render volatility on substances like carbohydrates or amino acids, that have several polar groups that they are non-volatile and generally decompose on heating.
• It allows the separations not possible with underivatized compounds.
• Compounds are detectable at very low levels with an ECD.

Acetic anhydride is a reagent utilized to form fragmentation-directing derivatives for GC/MS analysis.

アプリケーション

Learn more in the Product Information

Suitable for the derivatization of acetyl, acetaminophen, alcohols, aldoses and partially methylated aldoses, aldosterone, amines, amino acids, amino sugars (in polysaccharides), amino sugar methyl glycosides, 2-amino-2-deoxyhexoses, arginyl peptides, aryl sulfate esters, bile acids, carbamates, carbohydrates, cerebrosides, cystine and cysteine (in peptides), desmethyldoxepin, 3,4-dihydroxyphenylglycol, estrogens, glycitols, hexopyranosides, hexosamines, hydroxamic acids, hydroxyamines, n-hydroxycarbamates, hydroxy steroids, inositols, 4-methoxy and 3,4-dimethoxyphenethylamine, methyl ester, methyl(methyl O-methyl-a-D-glucopyranosid)uronates, nucleosides, nucleoside bases and sugars, partially methylated pentose and hexoes, peptides, phenolalkylamines, phenylethylamines, polysaccharide constituents, postaglandins A,B and E, serotonin, sialic acids, sugars, natural sugars and tryptamine.

その他情報

Reagent for acetic anhydride, acetyl, n-acetyl, n-acetyl-n, o-acetyl, acetate, aldononitrile acetate, aminoglycitol acetate, aryl acetate, permethyl acetyl, methyl ester, trifluoroacetyl, bis-trimethylsilyl, trimethylsilyl polyamino alcohol, and O-trimethylsilyl (TMS).

法的情報

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS05,GHS06
• シグナルワード: Danger
• 危険有害性情報: H226 - H302 - H314 - H330
• 注意書き: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 120.2 °F - closed cup
• 引火点(℃): 49 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter