52619

ヘキサメチルジシラザン

for GC derivatization, LiChropur^™, ≥99.0% (GC)

• 別名: HMDS
• 化学式: (CH₃)₃SiNHSi(CH₃)₃
• CAS番号: 999-97-3
• 分子量: 161.39
• Beilstein: 635752
• EC Number: 213-668-5
• MDL番号: MFCD00008259
• UNSPSCコード: 12000000
• PubChem Substance ID: 329757861
• NACRES: NA.22

特性

• グレード: for GC derivatization
• 品質水準: 100
• アッセイ: ≥99.0% (GC)
• フォーム: liquid
• 品質: LiChropur^™
• 反応適合性: reagent type: derivatization reagent; reaction type: Silylations
• テクニック: gas chromatography (GC): suitable
• 屈折率: n20/D 1.407 (lit.); n20/D 1.408
• bp: 125 °C (lit.)
• SMILES記法: C[Si](C)(C)N[Si](C)(C)C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• InChI Key: FFUAGWLWBBFQJT-UHFFFAOYSA-N

詳細

詳細

Hexamethyldisilazane (HMDS) is a commercially available, silylating agent, which is used as an alternative for the preparation of silyl ethers from hydroxyl compounds.

アプリケーション

Learn more in the Product Information

Hexamethyldisilazane is suitable for the derivatization of alcohols, U-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

It may be used as a derivatizing reagent for the analysis of bioamines and their acidic metabolites, phenol, hydroquinone and catechol in urine samples, mixtures of free fatty acids and metal soaps in paint samples using gas chromatography/mass spectrometry (GC/MS).

Suitable for the derivatization of alcohols, Υ-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.

特徴および利点

• HMDS is inexpensive and has a relatively low boiling point (124-127 °C).        
• It can be used without solvent but its silylating power can be increased by various (mostly acidic) catalysts.        
• The only reaction byproduct, ammonia, can leave the reaction mixture as the reaction goes to completion.

その他情報

重要なシリル化剤

Reagent for 2-hydroxypyrimidine, polytrimethylsilyloxy, trimethylsilyl and trimethylsilyl oximes.

法的情報

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06
• シグナルワード: Danger
• 危険有害性情報: H225,H302 + H332,H311,H412
• 注意書き: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 52.5 °F - closed cup
• 引火点(℃): 11.4 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter