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グレード
analytical standard
品質水準
製品種目
PESTANAL®
シェルフライフ
limited shelf life, expiry date on the label
テクニック
HPLC: suitable
gas chromatography (GC): suitable
アプリケーション
agriculture
environmental
forensics and toxicology
veterinary
フォーマット
neat
SMILES記法
Oc1ccc2[nH]c(nc2c1)-c3cscn3
InChI
1S/C10H7N3OS/c14-6-1-2-7-8(3-6)13-10(12-7)9-4-15-5-11-9/h1-5,14H,(H,12,13)
InChI Key
VNENJHUOPQAPAT-UHFFFAOYSA-N
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詳細
5-Hydroxythiabendazole present in excreta, eggs, edible tissues and milk is found to be the major metabolite of thiabendazole, an active ingredient in fungicidal preparations effective for plants. It can also be used as an anthelmintic drug, which is applicable both for humans and animals.
アプリケーション
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Thiabendazole and its metabolite 5-hydroxythiabendazole can undergo specific binding with monoclonal antibodies and can further undergo immobilization on agarose gels, which can find applications in immunoaffinity chromatography.
法的情報
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Aquatic Acute 1
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
33818-BULK:
33818-VAR:
33818-10MG:
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Metabolism of thiabendazole in laying hen and lactating goats
Chukwudebe.CA, et al.
Journal of Agricultural and Food Chemistry, 42, 2964-2969 (1994)
Concentrations of thiabendazole and parasite-specific IgG antibodies in the cerebrospinal fluid of a patient with disseminated strongyloidiasis.
J C Arroyo et al.
The Journal of infectious diseases, 156(3), 520-523 (1987-09-01)
M T Watts et al.
Journal of chromatography, 230(1), 79-86 (1982-06-11)
We have developed a rapid, sensitive and precise high-performance liquid chromatographic method using fluorescence detection for the simultaneous determination of thiabendazole and unconjugated 5-hydroxythiabendazole in serum. Sample pretreatment consists only of protein precipitation with acetonitrile containing the internal standard, 2-methylindole.
Immobilisation of thiabendazole specific antibodies on an agarose matrix for application in immunoaffinity chromatography
Horne E, et al.
Analyst, 124, 87-90 (1999)
A Cannavan et al.
Journal of chromatography. B, Biomedical sciences and applications, 718(1), 103-113 (1998-12-01)
A novel method is presented for the determination of thiabendazole and 5-hydroxythiabendazole in animal tissues. Samples are homogenised in buffer at pH=7.0, extracted with ethyl acetate and cleaned up using CN solid-phase extraction columns. Thiabendazole and 5-hydroxythiabendazole are separated chromatographically
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