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形状
powder
品質水準
組成
Dye content, 60%
λmax
407 nm (2nd)
570 nm
アプリケーション
diagnostic assay manufacturing
hematology
histology
保管温度
room temp
SMILES記法
[Na+].[Na+].[Na+].[Na+].CC(=O)Nc1ccc(c2cc(c(\N=N\c3ccc(\N=N/c4ccc(cc4)S([O-])(=O)=O)c5ccc(cc35)S([O-])(=O)=O)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O
InChI
1S/C28H21N5O14S4.4Na/c1-14(34)29-23-10-11-24(50(42,43)44)20-13-25(51(45,46)47)27(28(35)26(20)23)33-32-22-9-8-21(18-7-6-17(12-19(18)22)49(39,40)41)31-30-15-2-4-16(5-3-15)48(36,37)38;;;;/h2-13,35H,1H3,(H,29,34)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47);;;;/q;4*+1/p-4/b31-30-,33-32+;;;;
InChI Key
GMMAPXRGRVJYJY-OXYXOBGMSA-J
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関連するカテゴリー
アプリケーション
Brilliant Black BN has been used:
- in micronucleus and comet assays to evaluate its genotoxic effect.
- as a quenching agent in calcium mobilization assay.
- as a redox indicator in microbiological inhibition bioassay using Bacillus megaterium to detect tetracycline and macrolides in milk.
生物化学的/生理学的作用
[4-acetamido-5-hydroxy-6-[7-sulfonato-4-(4-sulfonatophenylazo)-1-naphtylazo], also known as food black 1, belongs to the group of azo dyes. Brilliant Black BN is widely used as a food dye and pharmaceutical excipient. In addition, it also acts as an allosteric modulator of the adenosine A1 and A3 receptors and is generally used within calcium mobilization assays to reduce extracellular fluorescence.
保管分類コード
11 - Combustible Solids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
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Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions.
Molecular Pharmacology, 77, 678-686 (2010)
Novel bioassay using Bacillus megaterium to detect tetracycline in milk
Revista Argentina de microbiologia, 48, 143-146 (2016)
The evaluation of the genotoxicity of two commonly used food colors: Quinoline Yellow (E 104) and Brilliant Black BN (E 151).
Cellular & Molecular Biology Letters, 9, 107-122 (2004)
Calcium Mobilisation Assay in Response to Chemokine Stimulation
Bio-protocol, 2 (2012)
Microbiological Method using Bacillus megaterium
with Fusidic Acid for Detection of Macrolides in Milk
with Fusidic Acid for Detection of Macrolides in Milk
Czech Journal of Food Sciences, 34, 9-15 (2016)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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