19606

ビオチン

tested according to Ph. Eur.

• 別名: Biotinum, D-ビオチン, Bios II, ビタミンB7, ビタミンH, 補酵素A
• 実験式（ヒル表記法）: C₁₀H₁₆N₂O₃S
• CAS番号: 58-85-5
• 分子量: 244.31
• Beilstein: 86838
• EC Number: 200-399-3
• MDL番号: MFCD00005541
• UNSPSCコード: 12352201
• PubChem Substance ID: 329751923
• NACRES: NA.21

特性

• 由来生物: synthetic
• 品質水準: 200
• 認証: tested according to Ph. Eur.
• mp: 231-233 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• SMILES記法: [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
• InChI Key: YBJHBAHKTGYVGT-ZKWXMUAHSA-N

詳細

詳細

Biotin, also called vitamin B7 or vitamin H is a water-soluble B complex vitamin, which contains an uredo ring fused by a tetrahydrothiophene ring. It is found in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.

アプリケーション

Biotin has been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

生物化学的／生理学的作用

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Biotin functions as an important cofactor for carboxylase enzymes in several metabolic pathways. It acts as a coenzyme in the metabolism of fatty acids, isoleucine and valine. Biotin is implicated in gluconeogenesis and citric acid cycle. It is involved in keratin synthesis and hence is used as a supplement for skin, hair and nail growth. Biotin promotes cell growth, production of fatty acids and the metabolism of fats and amino acids. It assists the transfer of carbon dioxide and also sustains a steady blood sugar level.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)