04573

チアミン 塩酸塩

tested according to Ph. Eur.

• 別名: Thiamio hydrochloridum, アノイリン 塩酸塩, ビタミンB₁ 塩酸塩
• 実験式（ヒル表記法）: C₁₂H₁₇ClN₄OS · HCl
• CAS番号: 67-03-8
• 分子量: 337.27
• Beilstein: 3851771
• EC Number: 200-641-8
• MDL番号: MFCD00012780
• UNSPSCコード: 12352209
• eCl@ss: 34058006
• PubChem Substance ID: 329747946
• NACRES: NA.26

特性

• 由来生物: synthetic
• 品質水準: 200
• 認証: USP/NF; tested according to Ph. Eur.
• アッセイ: 98.5-101.0% anhydrous basis
• フォーム: solid
• mp: 250 °C (dec.) (lit.)
• 溶解性: alcohol: soluble 1 gm in 100 ml (95%); alcohol: soluble 1 gm in 315 ml (Absolute); glycerol: soluble 1 gm in 18 ml; water: soluble 1 g/mL; benzene: insoluble; chloroform: insoluble; diethyl ether: insoluble; hexane: insoluble; methanol: very soluble; propylene glycol: soluble
• 保管温度: 2-8°C
• SMILES記法: CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
• InChI: 1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
• InChI Key: DPJRMOMPQZCRJU-UHFFFAOYSA-M

詳細

アプリケーション

Thiamine hydrochloride has been used as a keratin salts medium supplement for culturing log-phase fungus. It has also been used as a supplement of VB medium the minimal medium of Vogel and Bonner.

生物化学的／生理学的作用

Thiamine hydrochloride is a cheap, non-toxic and efficient catalyst for the synthesis of amidoalkyl naphthols. It inhibits the production of shikonin derivatives by suspension cultures of Lithospermum erythrorhizon. Additionally, thiamine hydrochloride addition to apple juice concentrates reduces its patulin content.

Thiamine hydrochloride is a hydrochloride salt form of thiamine (Vitamin B₁). It is crucial for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H319
• 注意書き: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)