おすすめの製品
由来生物
mouse
品質水準
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
1F3.9, monoclonal
フォーム
liquid
含まれません
preservative
交差性
human, rat, mouse
メーカー／製品名
Calbiochem®
保管条件
OK to freeze
avoid repeated freeze/thaw cycles
アイソタイプ
IgG
輸送温度
wet ice
保管温度
−70°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... PPARGC1A(10891)
詳細
Protein G purified mouse monoclonal antibody. Recognizes the ~113 kDa PGC-1α protein.
Recognizes the ~113 kDa PGC-1α protein in COS cells.
This Anti-PGC-1α Mouse mAb (1F3.9) is validated for use in Immunoblotting, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation for the detection of PGC-1α.
免疫原
A recombinant protein consisting of amino acids 1-120 of mouse PGC-1α
アプリケーション
Immunoblotting (1 g/ml)
Immunocytochemistry (5-10 g/ml)
Immunohistochemistry (5-10 g/ml)
Immunoprecipitation (1:100)
警告
Toxicity: Regulatory Review (Z)
物理的形状
In 50 mM PBS
アナリシスノート
Positive Control
Brown adipose tissue from mice exposed to cold
Brown adipose tissue from mice exposed to cold
その他情報
Chang, J.S., et al. 2010. J. Biol. Chem.285, 18039.
Zhang, Y. et al. 2009. J. Biol. Chem.284, 32813.
Lai, L., et al. 2008. Genes Dev.14, 1948.
Rodgers, J.T., et al. 2008. FEBS Lett.582, 46.
Mazzucotelli, A., et al. 2007. Diabetes10, 2467.
Nemoto, S., et al. 2005. J. Biol. Chem.16, 16456.
Zhang, Y. et al. 2009. J. Biol. Chem.284, 32813.
Lai, L., et al. 2008. Genes Dev.14, 1948.
Rodgers, J.T., et al. 2008. FEBS Lett.582, 46.
Mazzucotelli, A., et al. 2007. Diabetes10, 2467.
Nemoto, S., et al. 2005. J. Biol. Chem.16, 16456.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ST1203-100UL:
ST1203-100RUL:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Shino Nemoto et al.
The Journal of biological chemistry, 280(16), 16456-16460 (2005-02-18)
In lower organisms, increased expression of the NAD-dependent deacetylase Sir2 augments lifespan. The mechanism through which this life extension is mediated remains incompletely understood. Here we have examined the cellular effects of overexpression of SIRT1, the closest mammalian ortholog of
Ling Lai et al.
Genes & development, 22(14), 1948-1961 (2008-07-17)
Oxidative tissues such as heart undergo a dramatic perinatal mitochondrial biogenesis to meet the high-energy demands after birth. PPARgamma coactivator-1 (PGC-1) alpha and beta have been implicated in the transcriptional control of cellular energy metabolism. Mice with combined deficiency of
Ji Suk Chang et al.
The Journal of biological chemistry, 285(23), 18039-18050 (2010-03-31)
Peroxisome proliferator-activated receptor gamma co-activator-1alpha (PGC-1alpha) plays a central role in the regulation of cellular energy metabolism and metabolic adaptation to environmental and nutritional stimuli. We recently described a novel, biologically active splice variant of PGC-1alpha (NT-PGC-1alpha, amino acids 1-270)
Dorothy E Vatner et al.
Aging cell, 17(4), e12751-e12751 (2018-04-15)
Disruption of the regulator for G protein signaling 14 (RGS14) knockout (KO) in mice extends their lifespan and has multiple beneficial effects related to healthful aging, that is, protection from obesity, as reflected by reduced white adipose tissue, protection against
Joseph T Rodgers et al.
FEBS letters, 582(1), 46-53 (2007-11-27)
Energy homeostasis in mammals is achieved through tight regulation of tissue-specific metabolic pathways that become dysregulated in metabolic diseases including diabetes and obesity. At the molecular level, main nutrient and hormonal signaling pathways impinge on expression of genes encoding for
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