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Merck

MSCRMAG-42K

Millipore

MILLIPLEX® Mouse Soluble Cytokine Receptor Magnetic Bead Panel - Immunology Multiplex Assay

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

化学種の反応性

mouse

メーカー/製品名

Milliplex®

assay range

accuracy: 89-98%
standard curve range: 12.2-50,000 pg/mL
(sIL-1RI, sIL-1RII, sIL-2Rα, sIL-4R, sTNFRII)

standard curve range: 24.4-100,000 pg/mL
(sCD30, sgp130, sIL-6R, sRAGE, sVEGFR1, sVEGFR2, sVEGFR3)

standard curve range: 4.9-20,000 pg/mL
(sTNFRI)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Cytokine receptors constitute an integral part of the cytokine biology. Like cytokines, cytokine receptors are involved in normal physiological and pathological processes of almost all disease states. Soluble cytokine receptors naturally arise from genes encoding membrane-bound receptors or are direct derivatives of the receptors themselves. The discovery that soluble cytokine receptors are involved in regulating excessive inflammatory responses and modulating immune events has stimulated significant research interest in their potential role as immunotherapeutic agents. Many of these soluble cytokine receptors have the ability to inhibit the binding and biological activity of their cytokine ligands, making them very specific cytokine antagonists.

The MILLIPLEX® Mouse Soluble Cytokine Receptor Panel contains 13 metastasis biomarkers that have also been identified in a variety of therapeutic areas. Coupled with the Luminex® xMAP® platform in bead format, this panel enables researchers to focus on discovery with the advantage of simultaneous quantitative multiplex detection leading to speed and sensitivity.

Panel Type: Cytokines/Chemokines

アプリケーション

  • Analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4)
  • Recommended Sample type: serum, plasma and cell culture
  • Recommended Sample dilution: 1:5 diluted serum and plasma
  • Assay Run Time: Overnight
  • Research Category: Inflammation & Immunology

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

その他情報

Please contact Technical Service for linearity of dilution.
Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

ピクトグラム

Exclamation markEnvironment

シグナルワード

Warning

危険有害性の分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

ターゲットの組織

Respiratory system

保管分類コード

10 - Combustible liquids


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

MSCRMAG-42K-02:
MSCRMAG-42K-03C:
MSCRMAG-42K-06C:
MSCRMAG-42K-08:
MSCRMAG-42K-02C:
MSCRMAG-42K-05:
MSCRMAG-42K-09C:
MSCRMAG-42K-01C:
MSCRMAG-42K-01:
MSCRMAG-42K-04C:
MSCRMAG-42K-07C:
MSCRMAG-42K-04:
MSCRMAG-42K-10:
MSCRMAG-42K-06:
MSCRMAG-42K:
MSCRMAG-42K-10C:
MSCRMAG-42K-12:
MSCRMAG-42K-13C:
MSCRMAG-42K-11C:
MSCRMAG-42K-11:
MSCRMAG-42K-05C:
MSCRMAG-42K-13:
MSCRMAG-42K-07:
MSCRMAG-42K-08C:
MSCRMAG-42K-12C:
MSCRMAG-42K-03:
MSCRMAG-42K-09:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Damien Restagno et al.
PloS one, 11(8), e0162109-e0162109 (2016-08-31)
Sepsis is characterized by pro- and anti-inflammatory responses following infection. While inflammation is responsible for widespread organ damage, anti-inflammatory mediators lead to immunoparalysis increasing susceptibility to secondary infections (nosocomial pneumonia). We aimed to investigate the impact of bacterial load on
Katherine Young Bezold Lamm et al.
eLife, 7 (2018-01-09)
Healthy pregnancy depends on proper placentation-including proliferation, differentiation, and invasion of trophoblast cells-which, if impaired, causes placental ischemia resulting in intrauterine growth restriction and preeclampsia. Mechanisms regulating trophoblast invasion, however, are unknown. We report that reduction of Inverted formin 2
Susana Rodriguez et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(2), 2657-2676 (2020-01-08)
Local and systemic factors that influence renal structure and function in aging are not well understood. The secretory protein C1q/TNF-related protein 1 (CTRP1) regulates systemic metabolism and cardiovascular function. We provide evidence here that CTRP1 also modulates renal physiology in

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