MABT189

Anti-Delta3 Antibody, clone 1E7.2

clone 1E7.2, from mouse

• 別名: Delta-like protein 3, Drosophila Delta homolog 3, Delta3
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 1E7.2, monoclonal
• 交差性: human
• テクニック: flow cytometry: suitable; western blot: suitable
• アイソタイプ: IgMκ
• NCBIアクセッション番号: NP_058637
• UniProtアクセッション番号: Q9NYJ7
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... DLL3(10683)

詳細

詳細

DLL3, also known as Delta like ligand 3, is a transmembrane Delta-like protein principally found in the Golgi apparatus and endosomes where it promotes Notch family receptor degradation to inhibit primary neurogenesis. DLL3 is one of five DSL proteins that bind to the Notch receptor. Notch signaling pathways play key roles in cell-fate determination and differentiation in many tissues during embryonic and postnatal development. Notch ligands family members are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in the DLL3 gene causes autosomal recessive spondylocostal dysostosis.

免疫原

Linear peptide corresponding to human Delta3.

アプリケーション

Research Category
細胞骨格

Research Sub Category
ECMタンパク質

Flow Cytometry Analysis: 0.1 µg from a representative lot detected Delta3 in HEK293 cells.

This Anti-Delta3 Antibody, clone 1E7.2 is validated for use in WB, FC for the detection of Delta3.

品質

Evaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Delta3 on 10 µg of human liver tissue lysate.

ターゲットの説明

~65 kDa observed

物理的形状

Format: Purified

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Human liver tissue lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable