MABS416

Anti-ABCG5, clone 1B5E10 Antibody

clone 1B5E10, from mouse

• 別名: ATP-binding cassette sub-family G member 5, Sterolin-1, ABCG5
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 1B5E10, monoclonal
• 交差性: human
• テクニック: ELISA: suitable; flow cytometry: suitable; immunohistochemistry: suitable; western blot: suitable
• アイソタイプ: IgG1
• UniProtアクセッション番号: Q9H222
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ABCG5(64240)

詳細

詳細

ATP-binding cassette sub-family G member 5, also known as Sterolin-1, and encoded by the gene name ABCG5, plays an important role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. ABCG5 is localized too the membrane and is expressed in the liver, lower levels in the small intestine and colon. Mutations associated with ABCG5 is Sitosterolemia, which is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterols including cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile.

免疫原

Purified recombinant fragment of human ABCG5 expressed in E. Coli

アプリケーション

Anti-ABCG5, clone 1B5E10 Antibody is an antibody against ABCG5 for use in western blotting, IHC, flow cytometry & ELISA.

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected ABCG5 in cervical and rectum cancer tissues.

Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected ABCG5 in A549 cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).

品質

Evaluated by Western Blotting in HL7702, Raji and Jurkat cell lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ABCG5 in HL7702, Raji and Jurkat cell lysates.

ターゲットの説明

~70 kDa observed. Uncharacterized bands may be observed in some lysate(s).

関連事項

Replaces: MABN1076

物理的形状

Format: Purified

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable