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Merck
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Key Documents

MABS2156

Sigma-Aldrich

Anti-Thrombomodulin Antibody, clone 1009

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

抗体製品の状態

purified antibody

クローン

1009
monoclonal

精製方法

using protein G

化学種の反応性

human, rat, mouse

濃度

(Please refer to lot specific datasheet.)

テクニック

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable
western blot: suitable

アイソタイプ

IgG1κ

UniProtアクセッション番号

作用機序

| inhibits

詳細

Recombinant fragment corresponding to 241 amino acids corresponding to six EGF repeats from human Thrombomodulin.

特異性

Clone 1009 is a mouse monoclonal antibody that detects Thrombomodulin.

アプリケーション

Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution from a representative lot detected Thrombomodulin in human tonsil tissue sections.

ELISA Analysis: A representative lot detected Thrombomodulin in ELISA applicaitons (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Radioimmunoassay Analysis: A representative lot detected Thrombomodulin in Radioimmunoassay applications (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Inhibits Activity/Function Analysis: A representative lot of this blocked thrombin binding and reduced Protein C activation (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6).

Flow Cytometry Analysis: A representative lot detected Thrombomodulin in Flow Cytometry applications (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Western Blotting Analysis: A representative lot detected Thrombomodulin in Western Blotting applications. (Xu, J., et. al. (1999). J Biol Chem. 274(10):6704-10; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).

Immunocytochemistry Analysis: A representative lot detected Thrombomodulin in Immunocytochemistry applications (Campbell, J.E., et. al. (2010). Blood. 116(26):6082-91).

Immunohistochemistry (Paraffin) Analysis: A representative lot detected Thrombomodulin in Immunohistochemistry applications (Trotman, W.E., et. al. (2011). Histochem Cell Biol. 135(2):141-52).

品質

Evaluated by Immunohistochemistry (Paraffin) in human placenta tissue sections.

Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Thrombomodulin in human placenta tissue sections.

物性

~60.33 kDa calculated.

物理的形状

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

その他情報

Human, Rat.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

試験成績書(COA)

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