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Key Documents

MABN316

Sigma-Aldrich

Anti-SLC38A3 Antibody, clone 1A10.2

clone 1A10.2, from mouse

別名:

Sodium-coupled neutral amino acid transporter 3, N-system amino acid transporter 1, Na(+)-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, System N amino acid transporter 1

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

由来生物

mouse

品質水準

抗体製品の状態

purified antibody

抗体製品タイプ

primary antibodies

クローン

1A10.2, monoclonal

化学種の反応性

human

テクニック

immunohistochemistry: suitable
western blot: suitable

アイソタイプ

IgG2aκ

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... SLC38A3(10991)

詳細

The sodium-coupled neutral amino acid transporter 3 (SLC38A3) protein is a sodium-dependent amino acid/proton exchanger (also called an antiporter or counter transporter) SLC38A3 mediates the electrogenic cotransport of glutamine and sodium ions in exchange for protons. SLC38A3 can also transport the amino acids histidine, asparagine and alanine in place of protons. Some evidence exists that SLC38A3 may mediate amino acid transport in either direction under particular physiological conditions such as homeostatic stress like that seen in acidosis, and SLC38A3 plays a role in nitrogen metabolism and synaptic transmission by regulating the levels of sodium and the stimulatory amino acid glutamine. SLC38A3 is localized to the cell membrane and is widely expressed in many tissues, including heart, liver, brain, and prostate.

免疫原

GST-tagged recombinant protein corresponding to human SLC38A3.

アプリケーション

Research Category
ニューロサイエンス
Research Sub Category
発生シグナル伝達
Anti-SLC38A3 Antibody, clone 1A10.2 | MABN316 is an antibody against SLC38A3 Antibody for use in Western Blotting, Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SLC38A3 in human kidney tissue.

品質

Evaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SLC38A3 in 10 µg of human kidney tissue lysate.

ターゲットの説明

~60 kDa observed

物理的形状

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

その他情報

Concentration: Please refer to lot specific datasheet.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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