MABN119

Anti-KLF6 Antibody, clone 12A8.3

clone 12A8.3, from mouse

• 別名: Krueppel-like factor 6, B-cell-derived protein 1, Core promoter element-binding protein, GC-rich sites-binding factor GBF, Proto-oncogene BCD1, Suppressor of tumorigenicity 12 protein, Transcription factor Zf9
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 12A8.3, monoclonal
• 化学種の反応性: mouse, human
• テクニック: immunohistochemistry: suitable; western blot: suitable
• アイソタイプ: IgG2bκ
• NCBIアクセッション番号: NP_001153596
• UniProtアクセッション番号: Q99612
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... KLF6(1316)

詳細

詳細

KLF6 (Krueppel-like factor 6), is also known as BCD1, COPEB, CPBP and ST12. KLF6 contains zinc-finger domains and is thought to be a transcriptional activator binding to GC box motifs. KLF6 is involved in B-cell growth and development and has been shown to be highly expressed in placental cells as well as other tissues including the spleen, thymus, prostate, testis, small intestine and colon. KLF6 defects have been linked to gastric cancer (GASC) and prostate cancer (PC).

免疫原

GST-tagged recombinant protein corresponding to human KLF6.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
発生シグナル伝達

This KLF6 antibody is validated for use in WB & IHC for the detection of the KLF6 protein.

Western Blotting Analysis: 0.5 µg/mL from a representative lot detected KLF6 in 10 µg of human placenta tissue lysate.
Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected KLF6 in human placenta tissue.

品質

Evaluated by Western Blotting in NIH-3T3 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected KLF6 in 10 µg of NIH-3T3 cell lysate.

ターゲットの説明

~37 kDa observed. The calculated molecular weight is 32 kDa, however KLF6 has been shown at ~37 through ~40 kDa bands in western blots (Kimmeleman, A. C., et al. (2004). Oncogene. 23:5077-5083).

物理的形状

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
NIH-3T3 cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable