MABF301

Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1

clone 7B1.1, from mouse

• 別名: Interleukin-7, IL-7
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 7B1.1, monoclonal
• 化学種の反応性: human
• テクニック: flow cytometry: suitable; western blot: suitable
• アイソタイプ: IgG2aκ
• NCBIアクセッション番号: NP_000871
• UniProtアクセッション番号: P13232
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... IL7(3574)

詳細

詳細

The protein named IL-7, or interleukin 7 is a hematopoietic growth factor secreted by stromal cell in the bone marrow and thymus but also produced by many other cell types including keratinocytes, epithelial cells, hepatocytes and macrophage/dendritic cells but not by classical lymphocytes. IL7 is a cytokine that has multiple functions and is critical for proper T cell maturation and lymphoid cell survival, and its expression stimulates the proliferation of B cells, T cell and NK cells. IL-7 is detected by cells via its receptor and binding results in a cascade of signals important for T cell development and for T cell survival within the periphery, as well as memory T cells. IL-7 expression is upregulated in various lymphomas and leukemias and because of its effects on T cell development IL-7 is being examined as a therapeutic agent for transplantation studies and even latent viral infection studies.

免疫原

GST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.

アプリケーション

Flow Cytometry Analysis: 1 µg of this antibody detected recombinant Interleukin-7/IL-7 in Jurkat T and Raji B lymphocytes.

This Anti-Interleukin-7/IL-7 Antibody, clone 7B1.1 is validated for use in western blotting & flow cytometry for the detection of Interleukin-7/IL-7.

品質

Evaluated by Western Blotting in Interleukin 7 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected 0.5 µg of recombinant Interleukin-7/IL-7.

ターゲットの説明

~ 17 kDa observed

物理的形状

Format: Purified

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable