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由来生物
mouse
品質水準
抗体製品の状態
ascites fluid
抗体製品タイプ
primary antibodies
クローン
6C1, monoclonal
化学種の反応性
mouse, sheep, rat, human, chicken, Xenopus
メーカー／製品名
Chemicon®
テクニック
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
アイソタイプ
IgM
UniProtアクセッション番号
輸送温度
dry ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... DAG1(1605)
特異性
Cranin (dystroglycan), extracellular site, near the C-terminus of the alpha-subunit. The expression and localization of cranin varies considerably according to the cells physiologic state and differentiaion state. MAB371 recognizes the same peptide region as MAB373 but a different epitope.
免疫原
Epitope: aa572-604 of human sequence
Synthetic peptide corresponding to a.a. 572-604 of human cranin.
アプリケーション
Research Category
細胞骨格
細胞骨格
細胞骨格
細胞骨格
Research Sub Category
細胞骨格
ECMタンパク質
細胞骨格
ECMタンパク質
Immunohistochemistry on tissue fixed briefly with 0.5% glutaraldehyde, 2% PLP fixation, methanol or acetone. Prolonged fixation must be avoided. Traditional formalin is not recommended. Suggested working dilution 1:1-1:50.
Immunocytochemistry on neuron, astrocyte, smooth muscle, fibroblast and epithelial cell lines.
ELISA
Not suggested for use in Western blot.
Optimal working dilutions must be determined by end user.
Immunocytochemistry on neuron, astrocyte, smooth muscle, fibroblast and epithelial cell lines.
ELISA
Not suggested for use in Western blot.
Optimal working dilutions must be determined by end user.
This Anti-Cranin Antibody, aa572-604 of human sequence, clone 6C1 is validated for use in ELISA, IC, IH for the detection of Cranin.
物理的形状
Ascites Liquid.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MAB371:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Purificaiton of Cranin, a laminin binding membrane protein
Smalheiser, NR and Kim, E.
The Journal of Biological Chemistry, 270, 15425-15433 (1995)
B J Collins et al.
Endocrinology, 142(7), 3152-3162 (2001-06-21)
Dystroglycan is a high affinity laminin-binding glycoprotein originally described as a member of the dystrophin-associated glycoprotein complex in muscle. We have demonstrated the presence of dystroglycan in the thyroid using immunocytochemistry, immunoblots, ligand binding assays, and relative quantitative RT-PCR. In
X Li et al.
The Journal of cell biology, 153(4), 811-822 (2001-05-16)
Fibroblast growth factors and receptors are intimately connected to the extracellular matrix by their affinity to heparan sulfate proteoglycans. They mediate multiple processes during embryonic development and adult life. In this study, embryonic stem cell-derived embryoid bodies were used to
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