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化学種の反応性
human
品質水準
メーカー／製品名
Chemicon®
テクニック
activity assay: suitable
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
詳細
Chemicon Investigator Kits for Integrin Research are a cost-effective source of reagents for all investigators intimately involved with this expanding field of study. The Integrin Classics Investigator Kit contains several of Chemicon′s most popular integrin antibodies, and allows an initial screenings with small quantities of these antibodies. All antibodies in the Integrin Classics kit are available for purchase individually in larger sizes.
Integrins belong to a large family of cell surface proteins commonly referred to as glycoproteins. Integrins are composed of noncovalently associated alpha and beta subunits which make up heterodimers: the larger termed alpha chain and the smaller beta chain. At least 16 alpha subunits and 8 beta subunits are expressed, which can give rise to 22 different integrins. Integrins are thought to play critical roles in cell migration, differentiation, and survival. There is now considerable evidence that these transmembrane receptors play an important role in the regulation of gene expression and signal transduction. Excellent reviews of integrin structure, function, and ligand specificity may be found in: Hynes, R. 1992. Cell 69:11-25; Kramer, R. 1993. "Integrin Structure and Ligand Specificity in Cell-Matrix Interactions" in Molecular and Cellular Aspects of Basement Membranes. Academic Press.
Chemicon offers the Integrin Classics Investigator Kit for initial screenings for several well-studied integrins. The reagents in this kit are not application specific but rather may be used in a variety of procedures, depending upon the needs of the individual investigator.
Integrins belong to a large family of cell surface proteins commonly referred to as glycoproteins. Integrins are composed of noncovalently associated alpha and beta subunits which make up heterodimers: the larger termed alpha chain and the smaller beta chain. At least 16 alpha subunits and 8 beta subunits are expressed, which can give rise to 22 different integrins. Integrins are thought to play critical roles in cell migration, differentiation, and survival. There is now considerable evidence that these transmembrane receptors play an important role in the regulation of gene expression and signal transduction. Excellent reviews of integrin structure, function, and ligand specificity may be found in: Hynes, R. 1992. Cell 69:11-25; Kramer, R. 1993. "Integrin Structure and Ligand Specificity in Cell-Matrix Interactions" in Molecular and Cellular Aspects of Basement Membranes. Academic Press.
Chemicon offers the Integrin Classics Investigator Kit for initial screenings for several well-studied integrins. The reagents in this kit are not application specific but rather may be used in a variety of procedures, depending upon the needs of the individual investigator.
アプリケーション
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
構成
alphaV Mouse Monoclonal Antibody (Part No. MAB1953Z-20) - 1 tube, 20 μg.
beta1 Mouse Monoclonal Antibody (Part No. MAB1951Z-20)- 1 tube, 20 μg.
beta2 Mouse Monoclonal Antibody (Part No. MAB1962Z-20) - 1 tube, 20 μg.
alpha5beta1 Mouse Monoclonal Antibody (Part No. MAB1999-20) - 1 tube, 20 μg.
alphaVbeta3 Mouse Monoclonal Antibody (Part No. MAB 1976Z-20) -1 tube, 20 μg.
alphaVbeta5 Mouse Monoclonal Antibody (Part No. MAB1961Z-20)- 1 tube, 20 μg.
beta1 Mouse Monoclonal Antibody (Part No. MAB1951Z-20)- 1 tube, 20 μg.
beta2 Mouse Monoclonal Antibody (Part No. MAB1962Z-20) - 1 tube, 20 μg.
alpha5beta1 Mouse Monoclonal Antibody (Part No. MAB1999-20) - 1 tube, 20 μg.
alphaVbeta3 Mouse Monoclonal Antibody (Part No. MAB 1976Z-20) -1 tube, 20 μg.
alphaVbeta5 Mouse Monoclonal Antibody (Part No. MAB1961Z-20)- 1 tube, 20 μg.
物理的形状
This kit contains some of Chemicon′s most popular monoclonals to alphaV, beta1, beta2, alphaVbeta3, alpha5beta1, and alphaVbeta5. 20μg each.
保管および安定性
Store antibodies at -20°C.
Important Note: Due to the small volumes contained within the kit, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid entrapped i
Important Note: Due to the small volumes contained within the kit, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid entrapped i
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
保管分類コード
12 - Non Combustible Liquids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ECM435:
試験成績書（COA）
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