CBL1348

Anti-Integrin beta1 Antibody, clone HM beta 1.1

clone HM beta 1.1, from hamster

• 別名: CD29 antigen, Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, fibronectin receptor beta subunit, integrin VLA-4 beta subunit, integrin beta 1, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen ; ; CD29 includes MDF2,
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: hamster
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: HM beta 1.1, monoclonal
• 化学種の反応性: human, mouse
• テクニック: immunocytochemistry: suitable
• アイソタイプ: IgG
• NCBIアクセッション番号: NP_002202.2
• UniProtアクセッション番号: P09055
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ITGB1(3688) ; mouse ... Itgb1(16412)

詳細

詳細

Integrin beta 1is also known as CD29. It is a transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits, forming the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions such as hemostasis, embryonic development, wound repair, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion.

特異性

Other species have not been tested.

免疫原

Epitope: Full length

Purified mouse VLA-4 antigen

アプリケーション

Research Category
細胞骨格

Research Sub Category
インテグリン

Detect Integrin beta1 using this Anti-Integrin beta1 Antibody, clone HM beta 1.1 validated for use in IC.

品質

Routinely evaluated by immunocytochemistry on mouse NIH3T3, A431 cells.

ターゲットの説明

130 kDa

物理的形状

Protein G Purified

Format: Purified

Purified in PBS with 0.05% NaN3.

保管および安定性

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

アナリシスノート

Control
NIH3T3, A431

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable