ABS402

Anti-CDKL5 NT Antibody

from rabbit, purified by affinity chromatography

• 別名: Cyclin-dependent kinase-like 5, CDKL5
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse, rat
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_001019795
• UniProtアクセッション番号: Q3UTQ8
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Cdkl5(382253)

詳細

詳細

Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine-protein kinase that mediates phosphorylation of Methyl-CpG-binding protein 2 (MECP2). MECP2 is a chromosomal protein that binds to methylated DNA, specifically to a single methyl-CpG pair. MECP2 mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.

免疫原

GST-tagged recombinant protein corresponding to mouse CDKL5 near the N-terminus.

アプリケーション

Anti-CDKL5 NT Antibody is a highly specific rabbit polyclonal antibody, that targets Cyclin-dependent kinase-like 5 & has been tested in western blotting.

Western Blotting Analysis: A representative lot detected CDKL5 in mouse brain tissue expressing wild type CDKL5 and not in mouse brain tissue expressing knockout CDKL5.

品質

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected CDKL5 in 10 µg of rat brain tissue lysate.

ターゲットの説明

~ 115 kDa observed

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable