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Key Documents

ABS30

Sigma-Aldrich

Anti-Sulfenic Acid Modified Cysteine (2-Thiodimedone-Specific Ig) Antibody

serum, from rabbit

別名:

Sulfenic Acid Modified Cysteine (2-Thiodimedone-Specific Ig)

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

由来生物

rabbit

品質水準

抗体製品の状態

serum

抗体製品タイプ

primary antibodies

クローン

polyclonal

化学種の反応性

human, mouse, rat

化学種の反応性(ホモロジーによる予測)

all

テクニック

western blot: suitable

アイソタイプ

IgG

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

詳細

Protein sulfenic acid formation is a reversible post-translational modification that may be used to monitor protein oxidation on reactive cysteines within target proteins. This can be detected with protein sulfenic acid derivatised with dimedone.

特異性

This anitbody recognizes sulfenic acid modified proteins. Pan modification against all species.

免疫原

Linear peptide corresponding to sulfenic acid modified proteins.

アプリケーション

Anti-Sulfenic Acid Modified Cysteine (2-Thiodimedone-Specific Ig) Antibody detects level of Sulfenic Acid Modified Cysteine & has been published & validated for use in WB.
Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF. (Seo, YH, et al. (2009). PNAS. 106(38): 16163-16168.)

品質

Evaluated by Western Blot in rat ventricular myocyte lysate.

Western Blot Analysis: 01:1,000 dilution of this antibody detected sulfenic acid modified proteins on 10 µg of rat ventricular myocyte lysate.

ターゲットの説明

Pan antibody smear is expected.

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保管分類コード

10 - Combustible liquids

WGK

WGK 1


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

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文書ライブラリにアクセスする

Ester Zito et al.
Molecular cell, 48(1), 39-51 (2012-09-18)
Endoplasmic reticulum (ER) thiol oxidases initiate a disulfide relay to oxidatively fold secreted proteins. We found that combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1α, ERO1β, and PRDX4 compromised the extracellular matrix in mice and interfered with
Juliana Navarro-Yepes et al.
Molecular neurobiology, 53(8), 5229-5251 (2015-09-28)
Intracytoplasmic inclusions of protein aggregates in dopaminergic cells (Lewy bodies) are the pathological hallmark of Parkinson's disease (PD). Ubiquitin (Ub), alpha (α)-synuclein, p62/sequestosome 1, and oxidized proteins are the major components of Lewy bodies. However, the mechanisms involved in the
Angel Stanoev et al.
Cell systems, 7(3), 295-309 (2018-08-27)
The proto-oncogenic epidermal growth factor receptor (EGFR) is a tyrosine kinase whose sensitivity to growth factors and signal duration determines cellular behavior. We resolve how EGFR's response to epidermal growth factor (EGF) originates from dynamically established recursive interactions with spatially
Lianggong Ding et al.
Nature metabolism, 3(12), 1648-1661 (2021-12-15)
To liberate fatty acids (FAs) from intracellular stores, lipolysis is regulated by the activity of the lipases adipose triglyceride lipase (ATGL), hormone-sensitive lipase and monoacylglycerol lipase. Excessive FA release as a result of uncontrolled lipolysis results in lipotoxicity, which can

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