おすすめの製品
由来生物
rabbit
品質水準
結合体
CY3 conjugate
クローン
polyclonal
交差性
mouse, rat
メーカー/製品名
Neuro-Chrom
テクニック
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
詳細
Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a polyclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse methods, cell culture and immuno-histochemistry, giving researchers a convenient and specific qualitative and quantitative tool for studying neuronal morphology.
特異性
Cat. # ABN2300C is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons.
Reactivity with other species has not been determined.
免疫原
Epitope: Whole Neuron Marker
アプリケーション
Research Category
ニューロサイエンス
ニューロサイエンス
Research Sub Category
神経細胞及びグリアマーカー
神経細胞及びグリアマーカー
Neuro-Chrom Pan Neuronal Marker-Rabbit, Cy3 Conjugate is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC & IF.
品質
Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry.
物理的形状
Polyclonal antibody cocktail blend conjugated to Cy3 in PBS buffer with 15mg/mL BSA and 0.05% NaN3
保管および安定性
Maintain at 2-8°C for up to 1 year from date of receipt.
アナリシスノート
Control
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.
Rat E18 cortex primary neuron cell culture or mouse adult brain cryosections.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ABN2300C3:
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Zoeb Jiwaji et al.
Nature communications, 13(1), 135-135 (2022-01-12)
Alzheimer's disease (AD) alters astrocytes, but the effect of Aß and Tau pathology is poorly understood. TRAP-seq translatome analysis of astrocytes in APP/PS1 ß-amyloidopathy and MAPTP301S tauopathy mice revealed that only Aß influenced expression of AD risk genes, but both
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