ABD77

Anti-Dax1 Antibody

from rabbit, purified by affinity chromatography

• 別名: Nuclear receptor subfamily 0 group B member 1, DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1, AHC
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: rat, human
• テクニック: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBIアクセッション番号: NP_000466
• UniProtアクセッション番号: P51843
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NR0B1(190)

詳細

詳細

Dax-1 is an orphan nuclear receptor and is required for the normal development of the hypothalamic-pituitary-adrenal-gonadal axis formation. Defects in Dax-1 are the cause of X-linked adrenal hypoplasia congenital (XL-AHC); also known as X-linked Addison disease (AHX). Dax-1 also has a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency by acting as a negative regulator of Oct3/4 in ES cells.

特異性

75% Homologogous to Mouse Dax1

免疫原

KLH-conjugated linear peptide corresponding to the Region of Ligand binding of Human Dax1.

アプリケーション

Research Category
幹細胞研究

Research Sub Category
多能性及び初期分化

Evaluated by Immunohistochemistry in Human and Rat adrenal gland tissue. Immunohistochemsitry Analysis: A 1:1000 dilution of this antibody detected Dax1 in Human and Rat glioblastoma adrenal gland tissue.

This Dax1 antibody is validated for use in WB & IHC for the detection of the Dax1 protein.

品質

Evaluated by Western Blot in a Dax1 overexpressing HEK293 transfected cell line. Western Blot Analysis: A 1:2000 dilution of this antibody detected Dax1 in a Dax1 overexpressing HEK293 transfected cell line.

ターゲットの説明

~53 kDa observed

関連事項

Replaces: 04-445

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Dax1 overexpressing HEK293 transfected cell line

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable