ABC67

Anti-Mitochondrial fission 1 protein (Fis1) Antibody

from rabbit, purified by affinity chromatography

• 別名: FIS1 homolog, hFis1, Tetratricopeptide repeat protein 11, TPR repeat protein 11
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_057152
• UniProtアクセッション番号: Q9Y3D6
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FIS1(51024)

詳細

詳細

Mitochondrial fission 1 protein, hFIs1, is an overexpressed mammlian protein that is localized to the outer mitochondrial membrane of various cell types. It is involved in the fragmentation of the mitochondrial network and its perinuclear clustering, resulting in the release of cytochrome c from the mitochondrion, and apopotosis. It is known to mediate peroxisomal fission and also plays a critical role in histone function by demethylating Lys-4 of histone H3.

特異性

Other homologies: Rat and Mouse (83% sequence homology).

This antibody recognizes the cytoplasmic topological domain of Mitochondrial fission 1 protein.

免疫原

Epitope: Cytoplasmic topological domain

KLH-conjugated-linear peptide corresponding to the cytoplasmic topological domain of human Mitochondrial fission 1 protein.

アプリケーション

Research Category
アポトーシス及び癌

Research Sub Category
アポトーシス-追加

Detect Mitochondrial fission 1 protein (Fis1) using this Anti-Mitochondrial fission 1 protein (Fis1) Antibody validated for use in WB.

品質

Evaluated by Western Blot in Raji cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Mitochondrial fission 1 protein in 10 µg of Raji cell lysate.

ターゲットの説明

~17 kDa observed

物理的形状

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Raji cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable