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由来生物
rabbit
品質水準
抗体製品の状態
affinity purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
化学種の反応性
rat
メーカー／製品名
Chemicon®
テクニック
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
dry ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... AVPR2(554)
特異性
Arginine vasopressin receptor (AVP-V2), rat. The peptide used for immunization has no significant similarity with AVP V1a or V1b receptors.
免疫原
21 amino acid peptide from the 3rd cytoplasmic domain of rat AVP-V2 (Lolait et al. 1992; Fisov et al. 1994).
アプリケーション
Research Category
ニューロサイエンス
ニューロサイエンス
Research Sub Category
CNSによる代謝制御
ホルモン及び受容体
CNSによる代謝制御
ホルモン及び受容体
Anti-Arginine Vasopressin Receptor V2 Antibody is an antibody against Arginine Vasopressin Receptor V2 for use in ELISA, IH & WB.
Western blot: 1-10 μg/mL using ECL. An antibody raised against this peptide has detected a glycosylated band at ~62 kDa in membranes from rat inner medulla (Nonoguchi et al. 1995). N-Glycanase reduced the size to ~36 kDa (deglycosylated form).
Immunohistochemistry: 2-10 μg/mL on paraformaldehyde fixed tissue. AVP-V2 has been localized in terminal IMCD and other areas of rat kidney (Nonoguchi et al. 1995).
ELISA: 0.5-1.0 μg/mL using 1 μg/mL of control peptide to coat plate.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 2-10 μg/mL on paraformaldehyde fixed tissue. AVP-V2 has been localized in terminal IMCD and other areas of rat kidney (Nonoguchi et al. 1995).
ELISA: 0.5-1.0 μg/mL using 1 μg/mL of control peptide to coat plate.
Optimal working dilutions must be determined by the end user.
関連事項
Replaces: AB3512P
物理的形状
Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AB1797P:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
H Nonoguchi et al.
The Journal of clinical investigation, 96(4), 1768-1778 (1995-10-01)
We investigated immunohistochemical localization of V2 vasopressin receptor along the nephron using a specific polyclonal antibody. Staining was observed in some of thick ascending limbs and all of principal and inner medullary collecting duct (IMCD) cells. Not only basolateral but
D Firsov et al.
Pflugers Archiv : European journal of physiology, 429(1), 79-89 (1994-11-01)
Expression and regulation of vasopressin V2 and V1a receptors were studied at the mRNA level in the rat kidney. Two V2 mRNA variants were identified and shown to arise from a single gene by alternative splicing using one donor and
Shizuko Nagao et al.
Journal of the American Society of Nephrology : JASN, 17(8), 2220-2227 (2006-06-30)
Renal enlargement in polycystic kidney disease (PKD) is caused by the proliferation of mural epithelial cells and transepithelial fluid secretion into the cavities of innumerable cysts. Arginine vasopressin (AVP) stimulates the proliferation of human PKD cells in vitro via cAMP-dependent
Itaru Goto et al.
Circulation journal : official journal of the Japanese Circulation Society, 80(4), 989-997 (2016-03-01)
The expression of vasopressin type 2 receptor (V2R) in the lung, and the long-term effects of tolvaptan, a selective V2R antagonist, on pulmonary circulation and right ventricular (RV) remodeling in a pulmonary arterial hypertension (PAH) rat model were evaluated. Six-week-old
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