8.55049

H-Thr-Gly-NovaSyn^® TG resin

Novabiochem^®

• UNSPSCコード: 13111023
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: NovaSyn^® TG; Novabiochem^®
• 形状: beads
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis; reactivity: carbonyl reactive
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 官能基: amine
• 保管温度: 2-8°C

詳細

詳細

This resin is a useful tool for the synthesis of peptide aldehydes^[1]. Attachment of pre-formed amino acid aldehydes to this resin is effected by heating in 1% DIPEA in MeOH at 60 °C. Following chain extension using standard protocols, side-chain protecting groups can be removed with anhydrous TFA, prior to cleavage of the fully deprotected peptide aldehyde with MeCN/water/TFA. An analogous resin has been recently used to capture and purify peptide aldehydes generated by oxidation of peptide alcohols with IBX-polystyrene ^[2]. Novabiochem′s pre-loaded amino aldehyde resins can be found on page x.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

関連事項

Replaces: 04-12-3710

アナリシスノート

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc- Oxybenzaldehyde loaded resin): 0.15 - 0.35 mmol/g
Identity (of the substitution): passes test
Swelling Volume (in DMF): lot specific result
The base resin is amino PEG-PS-copolymer (90 µm).

法的情報

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable