8.52032

Fmoc-His(Trt)-OH

Novabiochem^®

• 別名: Fmoc-His(Trt)-OH, N-α-Fmoc-N-im-trityl-L-histidine
• 実験式（ヒル表記法）: C₄₀H₃₃N₃O₄
• CAS番号: 109425-51-6
• 分子量: 619.71
• MDL番号: MFCD00043332
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 400
• 製品種目: Novabiochem^®
• アッセイ: ≥97.0% (acidimetric); ≥98% (TLC); ≥99.0% (HPLC)
• フォーム: powder
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• mp: 130-145 °C (decomposition)
• アプリケーション: peptide synthesis
• 官能基: Fmoc
• 保管温度: −20°C (−15°C to −25°C)
• InChI: 1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m0/s1
• InChI Key: XXMYDXUIZKNHDT-QNGWXLTQSA-N

詳細

詳細

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of histidine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] P. Sieber, et al. (1987) Tetrahedron Lett., 28, 6031.

関連事項

Replaces: 04-12-1065

アナリシスノート

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 160 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His(Trt)-His(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-His-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable