8.21111

2-Thiazoline-2-thiol

for synthesis

• 別名: 2-Thiazoline-2-thiol, 2-Mercaptothiazoline
• 実験式（ヒル表記法）: C₃H₅NS₂
• CAS番号: 96-53-7
• 分子量: 119.21
• MDL番号: MFCD00126013
• UNSPSCコード: 12352113
• EC Index Number: 202-512-1
• NACRES: NA.22

特性

• 品質水準: 200
• 形状: powder
• 有効性: 300 mg/kg LD₅₀, oral (Rat)
• pH: 6-7 (20 °C, 10 g/L in H₂O)
• mp: 101-106 °C
• 保管温度: 2-30°C
• InChI: 1S/C3H5NS2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
• InChI Key: WGJCBBASTRWVJL-UHFFFAOYSA-N

詳細

アプリケーション

• Inducing apoptosis in melanoma cells: A study described a ruthenium(II) complex with 2-mercaptothiazoline ligand inducing selective cytotoxicity by causing DNA damage and apoptosis specifically in melanoma cells, highlighting its potential as a therapeutic agent in oncology (de Melo et al., 2024).
• Antimicrobial and synergistic activities: Thiazoline derivatives, including compounds related to 2-mercaptothiazoline, were studied for their antimicrobial and synergistic effects with conventional antibiotics against multidrug-resistant Staphylococcus aureus, presenting a potential strategy for enhancing antibiotic efficacy (Khan et al., 2020).
• Antimicrobial investigation of metal complexes: The antimicrobial properties of Cd(II) and Sn(II) complexes with 2-mercaptothiazoline were evaluated, underscoring the compound′s role in enhancing the bioactivity of metal-based therapeutics (Gaber et al., 2021).

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301
• 注意書き: P264 - P270 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral
• 保管分類コード: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable