528822

PARP Inhibitor XII

The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

• 別名: PARP Inhibitor XII, 3-(4-Chlorophenyl)quinoxaline-5-carboxamide
• 実験式（ヒル表記法）: C₁₅H₁₀ClN₃O
• CAS番号: 489457-67-2
• 分子量: 283.71
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: light brown
• 溶解性: DMSO: 10 mg/mL
• 輸送温度: ambient
• 保管温度: 2-8°C

詳細

詳細

A potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC₅₀ = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.

包装

Packaged under inert gas

警告

Toxicity: Irritant (B)

その他情報

Ishida, J., et al. 2006. Bioorg. Med. Chem.14, 1378.
Iwashita, A., et al. 2005. FEBS Lett.579, 1389.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable