5.06135

Venlafaxine Hydrochloride

• 別名: Venlafaxine Hydrochloride, SERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
• 実験式（ヒル表記法）: C₁₇H₂₇NO₂ · xHCl
• CAS番号: 99300-78-4
• 分子量: 277.40 (free base basis)
• MDL番号: MFCD03658865
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• アッセイ: ≥99% (HPLC)
• 品質水準: 100
• 形状: solid
• 有効性: 82 nM K_i
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white
• 溶解性: water: 100 mM; DMSO: 50 mM
• 保管温度: 2-8°C
• InChI: 1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
• InChI Key: QYRYFNHXARDNFZ-UHFFFAOYSA-N

詳細

詳細

A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (K_i = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.

生物化学的／生理学的作用

Primary Target
SERT/NET

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

その他情報

Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22.

Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS09
• 危険有害性情報: H411
• 注意書き: P273 - P391 - P501
• 危険有害性の分類: Aquatic Chronic 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable