219365

Coagulation Factor V, Human Plasma

Coagulation Factor V, Human Plasma, CAS 9001-24-5, is a native coagulation factor V that is cleaved by thrombin to yield activated Factor Va that is 50-fold greater activity than its precursor form.

• 別名: Coagulation Factor V, Human Plasma, Proaccelerin, Labile Factor, Ac-globulin, Ac-g
• CAS番号: 9001-24-5
• MDL番号: MFCD00792674
• UNSPSCコード: 12352202
• NACRES: NA.25

特性

• 品質水準: 100
• アッセイ: ≥95% (SDS-PAGE)
• フォーム: liquid
• 比活性: ≥20 units/mg protein (clotting assay)
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca²⁺, and membrane phospholipids are cofactors that form a "prothrombinase" complex with Factor X, enabling its proteolytic activation of prothrombin to thrombin.

Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca²⁺, and membrane phospholipids are cofactors which form a "prothrombinase" complex with Factor Xa, enabling its proteolytic activation of prothrombin to thrombin.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

物理的形状

In 50% glycerol/H₂O (v/v).

調製ノート

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

再構成

Following initial thaw, aliquot and freeze (-20°C). Do not store below -20°C.

アナリシスノート

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

その他情報

Walker, F.J. 1992. J. Biol. Chem.267, 19896.
Monkovic, D.D., and Tracy, P.B. 1990. J. Biol. Chem.265, 17132.
Krishnaswamy, S., et al. 1989. J. Biol. Chem.264, 3160.
Lee, C.D., and Mann, K.G. 1989. Blood73, 185.
Krieg, U.C., et al. 1987. Biochemistry26, 103.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2