208900

Calpastatin, Human, Recombinant, Domain I

Domain I of human calpastatin.

• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• 品質水準: 100
• 形状: lyophilized solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: aqueous buffer: 1 mg/mL; water: 1 mg/mL
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

An endogenous protease inhibitor that acts specifically on Calpain I (Cat. No. 208712), a Ca²⁺-dependent cysteine protease. Widely distributed in mammalian and avian cells. Has better inhibitory action than Calpain Inhibitor I (Cat. No. 208719) and Calpain Inhibitor II (Cat. No. 208721). Calpastatin corresponds to domain I of human calpastatin. The inhibitory sequence of human domain I consists of at least 18 amino acid residues.

Domain I of human calpastatin. Endogenous protease inhibitor that acts specifically on Calpain-1 (Cat. No. 208712). Exhibits greater inhibitory potency than calpain inhibitors I and II.

生物化学的／生理学的作用

50 nM completely inhibits the activity of 7.5 µg/ml calpain I

Cell permeable: no

Primary Target
calpain-1

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

アナリシスノート

homogeneous by SDS-PAGE

その他情報

Salamino, F., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1326.
Uemori, T., et al. 1990. Biochem. Biophys. Res. Commun. 166, 1485.
Asada, K., et al. 1989. J. Enzyme Inhib.3, 49.

法的情報

Not available for sale in Japan.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable