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Merck

178479

Sigma-Aldrich

Anti-Apolipoprotein E Goat pAb

liquid, Calbiochem®

別名:

Anti-ApoE antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

goat

品質水準

抗体製品の状態

serum

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

liquid

含みます

≤0.1% sodium azide as preservative

交差性

human, rat, mouse

メーカー/製品名

Calbiochem®

保管条件

OK to freeze
avoid repeated freeze/thaw cycles

アイソタイプ

IgG

輸送温度

wet ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

詳細

Anti-Apolipoprotein E, goat polyclonal, recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins. It is validated for ELISA, immunoprecipitation, and free-floating sections.
Goat polyclonal antibody supplied as serum that has been defibrinated, delipidized and dialyzed against a Tris-HCl buffer. Recognizes the apolipoprotein E protein.
Recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins.
  • Antibody Target Gene Symbol: APOE
  • Target Synonym: AD2, AI255918, APOE2, APOE4, APOEA, APOLIPOPROTEIN E, LDLCQ5, LPG, MGC1571
  • Entrez Gene Name: apolipoprotein E
  • Hu Entrez ID: 348 (Related Antibodies: NE1004)
  • Mu Entrez ID: 11816
  • Rat Entrez ID: 25728
  • 免疫原

    Human
    purified recombinant human apolipoprotein E

    アプリケーション

    ELISA (1:8000)

    Immunoprecipitation (see comments)

    Free Floating Sections (see application references)

    包装

    Please refer to vial label for lot-specific concentration.

    警告

    Toxicity: Standard Handling (A)

    物理的形状

    In 500 mM NaCl, 50 mM Tris-HCl, pH 7.5.

    再構成

    Following initial thaw, aliquot and freeze (-20°C).

    その他情報

    Monospecific as determined by immunoelectrophoresis (IEP) against twice concentrated pooled human serum. This antibody has also been reported to work with immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.

    法的情報

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    保管分類コード

    10 - Combustible liquids

    WGK

    WGK 1

    引火点(°F)

    Not applicable

    引火点(℃)

    Not applicable


    適用法令

    試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

    Jan Code

    178479-UL:
    178479-5ML:
    178479-500UL:
    178479-0ML:


    試験成績書(COA)

    製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

    以前この製品を購入いただいたことがある場合

    文書ライブラリで、最近購入した製品の文書を検索できます。

    文書ライブラリにアクセスする

    Emilie L Castranio et al.
    Neurobiology of disease, 105, 1-14 (2017-05-16)
    Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
    Suzanne E Wahrle et al.
    The Journal of biological chemistry, 279(39), 40987-40993 (2004-07-23)
    ABCA1 is an ATP-binding cassette protein that transports cellular cholesterol and phospholipids onto high density lipoproteins (HDL) in plasma. Lack of ABCA1 in humans and mice causes abnormal lipidation and increased catabolism of HDL, resulting in very low plasma apoA-I
    Michael Landowski et al.
    Proceedings of the National Academy of Sciences of the United States of America, 116(9), 3703-3711 (2019-02-28)
    One of the strongest susceptibility genes for age-related macular degeneration (AMD) is complement factor H (CFH); however, its impact on AMD pathobiology remains unresolved. Here, the effect of the principal AMD-risk-associated CFH variant (Y402H) on the development and progression of
    Ema Ozaki et al.
    Experimental eye research, 217, 108953-108953 (2022-01-30)
    As the resident immune cells in the retina, microglia play important homeostatic roles in retinal immune regulation and neuroprotection. However, chronic microglia activation is a common hallmark of many degenerative retinal diseases. The semi-synthetic tetracycline antibiotic, minocycline, appears to inhibit
    Shan-May Yong et al.
    Scientific reports, 4, 6580-6580 (2014-10-11)
    The effect of ApoE on NMDAR-dependent ERK/CREB signaling is isoform-dependent, and ApoE4 accelerates memory decline in ageing. However, this isoform-dependent function on neuronal signaling during ageing is unclear. In this study, we have examined NMDAR-associated ERK/CREB signal transduction in young

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