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由来生物
goat
品質水準
抗体製品の状態
serum
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
liquid
含みます
≤0.1% sodium azide as preservative
交差性
human, rat, mouse
メーカー／製品名
Calbiochem®
保管条件
OK to freeze
avoid repeated freeze/thaw cycles
アイソタイプ
IgG
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
詳細
Anti-Apolipoprotein E, goat polyclonal, recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins. It is validated for ELISA, immunoprecipitation, and free-floating sections.
Goat polyclonal antibody supplied as serum that has been defibrinated, delipidized and dialyzed against a Tris-HCl buffer. Recognizes the apolipoprotein E protein.
Recognizes human apolipoprotein E. Does not cross-react with other apolipoproteins.Antibody Target Gene Symbol: APOE Target Synonym: AD2, AI255918, APOE2, APOE4, APOEA, APOLIPOPROTEIN E, LDLCQ5, LPG, MGC1571 Entrez Gene Name: apolipoprotein E Hu Entrez ID: 348 (Related Antibodies: NE1004) Mu Entrez ID: 11816 Rat Entrez ID: 25728
免疫原
Human
purified recombinant human apolipoprotein E
アプリケーション
ELISA (1:8000)
Immunoprecipitation (see comments)
Free Floating Sections (see application references)
Immunoprecipitation (see comments)
Free Floating Sections (see application references)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
物理的形状
In 500 mM NaCl, 50 mM Tris-HCl, pH 7.5.
再構成
Following initial thaw, aliquot and freeze (-20°C).
その他情報
Monospecific as determined by immunoelectrophoresis (IEP) against twice concentrated pooled human serum. This antibody has also been reported to work with immunoprecipitation. Variables associated with assay conditions will dictate the proper working dilution.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
178479-UL:
178479-5ML:
178479-500UL:
178479-0ML:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Emilie L Castranio et al.
Neurobiology of disease, 105, 1-14 (2017-05-16)
Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
Suzanne E Wahrle et al.
The Journal of biological chemistry, 279(39), 40987-40993 (2004-07-23)
ABCA1 is an ATP-binding cassette protein that transports cellular cholesterol and phospholipids onto high density lipoproteins (HDL) in plasma. Lack of ABCA1 in humans and mice causes abnormal lipidation and increased catabolism of HDL, resulting in very low plasma apoA-I
Michael Landowski et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(9), 3703-3711 (2019-02-28)
One of the strongest susceptibility genes for age-related macular degeneration (AMD) is complement factor H (CFH); however, its impact on AMD pathobiology remains unresolved. Here, the effect of the principal AMD-risk-associated CFH variant (Y402H) on the development and progression of
Ema Ozaki et al.
Experimental eye research, 217, 108953-108953 (2022-01-30)
As the resident immune cells in the retina, microglia play important homeostatic roles in retinal immune regulation and neuroprotection. However, chronic microglia activation is a common hallmark of many degenerative retinal diseases. The semi-synthetic tetracycline antibiotic, minocycline, appears to inhibit
Shan-May Yong et al.
Scientific reports, 4, 6580-6580 (2014-10-11)
The effect of ApoE on NMDAR-dependent ERK/CREB signaling is isoform-dependent, and ApoE4 accelerates memory decline in ageing. However, this isoform-dependent function on neuronal signaling during ageing is unclear. In this study, we have examined NMDAR-associated ERK/CREB signal transduction in young
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