171372

Amphiregulin, Human, Recombinant

Amphiregulin, Human, Recombinant, consisting of amino acids 101-198 and is expressed in E. coli. Stimulates the proliferation of various human and mouse keratinocytes.

• 別名: Schwannoma-derived growth factor (SDGF)
• UNSPSCコード: 12352203
• NACRES: NA.77

特性

• リコンビナント: expressed in E. coli
• 品質水準: 100
• アッセイ: ≥97% (SDS-PAGE)
• 形状: liquid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 不純物: <1.0 EU/μg protein Endotoxin
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

Recombinant, human amphiregulin (AR) consisting of amino acids 101-198 and expressed in E. coli. Human amphiregulin is able to stimulate the proliferation of various human and mouse keratinocytes, mammary epithelial cells, and some fibroblasts. Shown to be an autocrine growth factor, amphiregulin is also a growth inhibitor for various tumor cells and can bind to the EGF receptor.

生物化学的／生理学的作用

ED₅₀ = 5-15 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.

警告

Toxicity: Standard Handling (A)

物理的形状

Lyophilized from 0.2 µm sterile-filtered PBS, BSA.

再構成

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3