1.04967

Potassium cyanide

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• 別名: Potassium cyanide, Cyanogen potassium
• 実験式（ヒル表記法）: CKN
• CAS番号: 151-50-8
• 分子量: 65.12
• MDL番号: MFCD00011397
• UNSPSCコード: 12352302
• EC Index Number: 205-792-3
• NACRES: NA.21

特性

• グレード: ACS reagent
• 品質水準: 300
• 認証: reag. ISO; reag. Ph. Eur.
• 製品種目: EMSURE^®
• アッセイ: ≥97% (silver nitrate titration)
• 形状: solid
• 有効性: 7.49 mg/kg LD₅₀, oral (Rat); 14.29 mg/kg LD₅₀, skin (Rabbit)
• pH: 11-12 (20 °C, 20 g/L in H₂O)
• bp: 1625 °C/1013 hPa
• mp: 634 °C
• 密度: 1.55 g/cm³ at 20 °C
• かさ密度: 750 kg/m³
• 微量陰イオン: chloride (Cl^-): ≤0.02%; phosphate (PO₄^3-): ≤0.005%; sulfate (SO₄^2-): ≤0.01%; sulfide (S^2-): ≤0.0005%; thiocyanate (SCN^-): ≤0.01%
• 微量陽イオン: Fe: ≤0.01%; Na: ≤0.5%; Pb: ≤0.0002%
• 保管温度: no temp limit
• InChI: 1S/CN.K/c1-2;/q-1;+1
• InChI Key: NNFCIKHAZHQZJG-UHFFFAOYSA-N

詳細

アプリケーション

• Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.: The research identifies iminium intermediates in the metabolism of tepotinib using liquid chromatography-mass spectrometry. Potassium cyanide is utilized to trap reactive intermediates, providing insights into drug metabolism pathways (Abdelhameed et al., 2020).


• Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.: This paper describes the synthesis of stable-isotope-labeled compounds using potassium cyanide in the synthesis process to understand the chemical structure and reactivity of these labeled compounds (Cao et al., 2020).


• Carbon-13 synthesis and NMR spectroscopic geometric isomer evaluation to support the filing of teriflunomide.: The study involves the synthesis of carbon-13 labeled teriflunomide and its isomers, using potassium cyanide in the synthetic pathway. The NMR spectroscopic analysis helped in the evaluation of geometric isomers (Kurz et al., 2021).


• A hybrid lipid membrane coating "shape-locks" silver nanoparticles to prevent surface oxidation and silver ion dissolution.: This research develops a hybrid lipid membrane to stabilize silver nanoparticles, using potassium cyanide in the analytical phase to measure the prevention of silver ion dissolution and oxidation (Miesen et al., 2020).

関連事項

Replaces: PX1435; PX1435-5; PX1435-1; PX1435-20

アナリシスノート

Assay (argentometric): ≥ 97.0 %
Chloride (Cl): ≤ 0.02 %
Phosphate (PO₄): ≤ 0.005 %
Sulfate (SO₄): ≤ 0.01 %
Sulphide (S): ≤ 0.0005 %
Thiocyanate (SCN): ≤ 0.01 %
Fe (Iron): ≤ 0.01 %
Na (Sodium): ≤ 0.5 %
Pb (Lead): ≤ 0.0002 %
Corresponds to ACS,Reag. Ph Eur

法的情報

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06,GHS08,GHS05,GHS09
• シグナルワード: Danger
• 危険有害性情報: H290,H300 + H310 + H330,H372,H410
• 注意書き: P262 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
• 危険有害性の分類: Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1
• ターゲットの組織: Thyroid
• 補足的ハザード: EUH032
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable