おすすめの製品
由来生物
rabbit
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
polyclonal
化学種の反応性
human
メーカー／製品名
Upstate®
テクニック
immunocytochemistry: suitable
western blot: suitable
アイソタイプ
IgG
GenBankアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ATRIP(84126)
詳細
Antibody recognizing ATR-Interacting Protein
特異性
ATRIP
免疫原
GST fusion protein corresponding to residues 1-181 of human ATR interacting protein (ATRIP)
アプリケーション
Research Category
エピジェネティクス及び核内機能分子
エピジェネティクス及び核内機能分子
Research Sub Category
細胞周期、DNA複製及び修復
細胞周期、DNA複製及び修復
Detect ATRIP with Anti-ATRIP Antibody (Rabbit Polyclonal Antibody), that has been shown to work in WB, ICC.
品質
Routinely evaluated by immunoblot on modified RIPA lysates from HEK293, HeLa and U20S cells
ターゲットの説明
85kDa
物理的形状
Protein G Purified
70% storage buffer (0.05M Tris-glycine, 0.025M sodium phosphate, pH 7.4, 0.15M NaCl, 0.035% sodium azide) and 30% glycerol
Format: Purified
保管および安定性
2 years at -20°C
法的情報
GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
D Cortez et al.
Science (New York, N.Y.), 294(5547), 1713-1716 (2001-11-27)
The checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3 related) transduce genomic stress signals to halt cell cycle progression and promote DNA repair. We report the identification of an ATR-interacting protein (ATRIP) that is phosphorylated by ATR
Lee Zou et al.
Science (New York, N.Y.), 300(5625), 1542-1548 (2003-06-07)
The function of the ATR (ataxia-telangiectasia mutated- and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex is crucial for the cellular response to replication stress and DNA damage. Here, we show that replication protein A (RPA), a protein complex that associates with
Qiang Li et al.
PloS one, 5(10), e13732-e13732 (2010-11-10)
H3K9 trimethylation (H3K9me3) and binding of PcG repressor complex-1 (PRC1) may play crucial roles in the epigenetic silencing of the p16 gene. However, the mechanism of the initiation of this trimethylation is unknown. In the present study, we found that
Janna Luessing et al.
iScience, 25(7), 104536-104536 (2022-06-28)
Abscission, the final stage of cytokinesis, occurs when the cytoplasmic canal connecting two emerging daughter cells is severed either side of a large proteinaceous structure, the midbody. Here, we expand the functions of ATR to include a cell-cycle-specific role in
Richard O Adeyemi et al.
Journal of virology, 88(17), 10189-10199 (2014-06-27)
The ATR kinase has essential functions in maintenance of genome integrity in response to replication stress. ATR is recruited to RPA-coated single-stranded DNA at DNA damage sites via its interacting partner, ATRIP, which binds to the large subunit of RPA.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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