07-1512

Anti-phospho-WAVE2 (Ser343) Antibody

from rabbit, purified by affinity chromatography

• 別名: SCAR2, WASF2, dJ393P12.2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human, monkey
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_008921
• UniProtアクセッション番号: Q9Y6W5
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer343)
• 遺伝子情報: human ... WASF2(10163)

詳細

詳細

Wiskott-Aldrich Syndrome Protein (WASP)-family Protein Member 2 (known as WAVE2) is found in many cells and tissues, with strong expression in peripheral blood leukocytes. WAVE2 is involved in signaling RTKs and small GTPases. As a whole, the WAVE family of proteins have a general function for regulating the actin cytoskeleton in various tissues.

特異性

This antibody recognizes WAVE2 phosphorylated at Ser343.

免疫原

Epitope: Phosphorylated Ser343

KLH-conjugated linear peptide corresponding to human WAVE2 phosphorylated at Ser343.

アプリケーション

Research Category
細胞骨格

Research Sub Category
細胞骨格シグナル伝達

Anti-phospho-WAVE2 (Ser343) Antibody detects level of phospho-WAVE2 (Ser343) & has been published & validated for use in WB.

Western Blot Analysis: A previous lot of this antibody was used to detect endogenous phospho-WAVE2 (Ser343) in COS-7 and HMECs following EGF stimulation ± pretreatment with U0126 (Mendoza, M.C., et al. (2011). Mol Cell. 41(6):661-671).

品質

Evaluated by Western Blot in COS-7+EGF cell lysates untreated and lambda phosphatase-treated.

Western Blot Analysis: A 1:500 dilution of this antibody detected phospho-WAVE2 (Ser343) in 10 µg of COS-7+EGF cell lysates untreated and lambda phosphatase treated.

ターゲットの説明

~75 kDa observed.
An uncharacterized band appears at ~103 kDa in some lysates.

物理的形状

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
COS-7+EGF cell lysates untreated and lambda phosphatase treated.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable