05-806-AF647

Anti-phospho Histone H3 (Ser10), clone 3H10, Alexa Fluor^™ 647 Antibody

clone 3H10, from mouse, ALEXA FLUOR^™ 647

• 別名: H3S10P, Histone H3 (phospho Ser10), H3 histone, family 3A, H3.3A, H3 histone, family 3B, H3.3B
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 647
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 3H10, monoclonal
• 交差性: human
• テクニック: immunocytochemistry: suitable
• NCBIアクセッション番号: NM_003493
• UniProtアクセッション番号: Q16695
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer10)
• 遺伝子情報: human ... HIST1H3F(8968)

詳細

詳細

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 05-806.

免疫原

Linear peptide corresponding to Histone H3 phosphorylated at Ser10.

アプリケーション

Research Category
エピジェネティクス及び核内機能分子

Research Sub Category
ヒストン

This Anti-phospho Histone H3 (Ser10) antibody, clone 3H10, Alexa Fluor^™ 647 is a purified mouse monoclonal for detection of Histone H3 phosphorylated at serine 10.
This mAb is fluorescently labeled and validated for use in IC. The unconjugated version has been proven in FC, ICC, IF, PIA, WB, Mplex.

品質

Evaluated by Immunocytochemistry Analysis in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected phospho Histone H3 (Ser10) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

ターゲットの説明

~17 kDa observed (Refer to Cat. No. 05-806)

物理的形状

Protein G Purified

Purified mouse conjugated antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% Sodium Azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

法的情報

ALEXA FLUOR is a trademark of Life Technologies

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable