890704C

18:1 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890704C

• 別名: 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• 実験式（ヒル表記法）: C₄₆H₈₉NO₈PCl
• CAS番号: 474945-24-9
• 分子量: 850.63
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 形状: liquid
• 包装: pkg of 1 × 2.5 mL (890704C-25mg); pkg of 1 × 4 mL (890704C-100mg); pkg of 2 × 4 mL (890704C-200mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 890704C
• 濃度: 10 mg/mL (890704C-25mg); 25 mg/mL (890704C-100mg); 25 mg/mL (890704C-200mg)
• 脂質タイプ: transfection; cationic lipids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)OCC.[Cl-]

詳細

詳細

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) is a cationic alkylated phospholipid.

アプリケーション

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (18:1 EPC (Cl Salt)) is suitable:

• for composing lipid shell to prepare lipopolyplex/mRNA vaccine
• in solvent-assisted preparation of supported lipid bilayers
• along with 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) in mixed liposomes as colloidal vectors for physicochemical study of the DNA compaction
• to formulate the lipid nanoparticle (LNP1) to enhance intracellular delivery mediated by shock waves

生物化学的／生理学的作用

1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (18:1 EPC) serves as a transfection reagent. 18:1 EPC is applicable in liposomes and lipoplexes. It is a potential vector in gene therapy.

包装

5 mL Clear Glass Sealed Ampule (890704C-100mg)

5 mL Clear Glass Sealed Ampule (890704C-200mg)

5 mL Clear Glass Sealed Ampule (890704C-25mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302,H315,H319,H331,H336,H351,H361d,H372
• 注意書き: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• ターゲットの組織: Liver,Kidney, Respiratory system
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 引火点(°F): does not flash
• 引火点(℃): does not flash