857324P

17:0 Cyclic LPA

Avanti Research^™ - A Croda Brand 857324P, powder

• 別名: 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt)
• 実験式（ヒル表記法）: C₂₀H₄₂NO₆P
• CAS番号: 2260669-82-5
• 分子量: 423.52
• UNSPSCコード: 51191904
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: powder
• 包装: pkg of 1 × 1 mg (857324P-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 857324P
• 脂質タイプ: phospholipids; cardiolipins
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCCC)=O)CO1.[NH4+]
• InChI: 1S/C20H39O6P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(21)24-17-19-18-25-27(22,23)26-19;/h19H,2-18H2,1H3,(H,22,23);1H3/t19-;/m1./s1
• InChI Key: QQOXNBRKDUFLHW-FSRHSHDFSA-N

詳細

詳細

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate.

アプリケーション

17:0 Cyclic LPA or 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of cyclic lysophosphatidic acid (LPA) esters in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS).

生物化学的／生理学的作用

cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

包装

5 mL Amber Glass Screw Cap Vial (857324P-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• 引火点(°F): No data available
• 引火点(℃): No data available