おすすめの製品
アッセイ
>99% (TLC)
フォーム
powder
包装
pkg of 1 × 1 mg (810192P-1mg)
メーカー／製品名
Avanti Research™ - A Croda Brand 810192P
輸送温度
dry ice
保管温度
−20°C
詳細
Phosphatidylserine (PS) is a membrane phospholipid enriched in the cytosolic leaflet of plasma membrane. It comprises 2-10% of total phospholipids. NBD PS is a flurosently labelled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.
アプリケーション
16:0-06:0 NBD PS has been used as a labelled translocase to detect ATP-dependent translocation across late Golgi membranes. It is also suitable for analysis of phospholipid scramblase 1 (PLSCR1) scrambling in proteoliposomes and to determine enzyme specificity of lipoteichoic acid synthase enzyme (LtaS).
16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) has been used in the 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) − phospholipase (PL) translocation assay to characterize an ATP-dependent flippase activity in yeast Golgi membranes. It may be used: to detect vesicular stomatitis virus G (VSV G) protein mediated cell-cell fusion, measure the enzyme substrate specificity of lipoteichoic acid (LTA) synthase (LtaS), in liposomes to determine the role of phospholipid scramblase 1 (PLSCR1) in phospholipid scrambling.
生物化学的／生理学的作用
Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components. It serves as an essential factor in the clearance of apoptotic cells. It is associated with cognitive disability in Alzheimer′s disease.
包装
5 mL Amber Glass Screw Cap Vial (810192P-1mg)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
810192P-1MG:
810192P-VAR:
810192P-BULK:
最新バージョンのいずれかを選択してください：
An Unrecognized Function of Cholesterol: Regulating the Mechanism Controlling Membrane Phospholipid Asymmetry
Arashiki N, et al.
Biochemistry, 55(25), 3504-3504 (2016)
Measuring translocation of fluorescent lipid derivatives across yeast Golgi membranes
Natarajan P, et al.
Methods, 39(2), 163-168 (2006)
Osmotic stress adaptation in Lactobacillus casei BL23 leads tostructural changes in the cell wall polymer lipoteichoic acid
Palomino MM, et al.
Microbiology, 159(11), 2416-2426 (2013)
Mirka E Wörmann et al.
Molecular microbiology, 79(3), 566-583 (2011-01-25)
Lipoteichoic acid (LTA) is an important cell wall polymer in Gram-positive bacteria. The enzyme responsible for polyglycerolphosphate LTA synthesis is LtaS, first described in Staphylococcus aureus. Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis.
Maria Karatsa-Dodgson et al.
Journal of bacteriology, 192(20), 5341-5349 (2010-08-17)
Lipoteichoic acid (LTA) is an important cell wall component of Gram-positive bacteria. The key enzyme responsible for polyglycerolphosphate lipoteichoic acid synthesis in the Gram-positive pathogen Staphylococcus aureus is the membrane-embedded lipoteichoic acid synthase enzyme, LtaS. It is presumed that LtaS
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）