QBD10850

Thiol-dPEG^®₁₂-acid

>95% (HPLC)

• 別名: CT(PEG)₁₂, Carboxy-PEG-Thiol, Carboxy-PEG₁₂-Thiol, HS-PEG₁₂-COOH, Thiol-PEG₁₂-acid
• 実験式（ヒル表記法）: C₂₇H₅₄O₁₄S
• 分子量: 634.77
• MDL番号: MFCD21363238
• UNSPSCコード: 12162002
• NACRES: NA.22

特性

• アッセイ: >95% (HPLC)
• 形状: solid or viscous liquid
• 反応適合性: reaction type: Pegylations
• ポリマー構造: shape: linear; functionality: heterobifunctional
• 輸送温度: ambient
• 保管温度: −20°C

詳細

特徴および利点

Thiol-dPEG₁₂-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long.

法的情報

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable