QBD10304

m-dPEG^®₂₄-NHS ester

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₅₄H₁₀₃NO₂₈
• 分子量: 1214.39
• MDL番号: MFCD11041155
• UNSPSCコード: 12352108
• PubChem Substance ID: 329823911
• NACRES: NA.22

特性

• アッセイ: >90%
• フォーム: solid or viscous liquid
• 反応適合性: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• ポリマー構造: shape: linear; functionality: monofunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
• InChI: 1S/C54H103NO28/c1-59-6-7-61-10-11-63-14-15-65-18-19-67-22-23-69-26-27-71-30-31-73-34-35-75-38-39-77-42-43-79-46-47-81-50-51-82-49-48-80-45-44-78-41-40-76-37-36-74-33-32-72-29-28-70-25-24-68-21-20-66-17-16-64-13-12-62-9-8-60-5-4-54(58)83-55-52(56)2-3-53(55
• InChI Key: VACCUKVGLYJBJU-UHFFFAOYSA-N

詳細

特徴および利点

The m-dPEG^®₂₄-NHS ester series of products provide a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. The number after the dPEG^® is the specific number of repeat units in the linear chain. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₂₄-NHS (N-hydroxysuccinimide) ester reacts with amines.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable