QBD10289

m-dPEG^®₁₂-MAL

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₃₂H₅₈N₂O₁₅
• CAS番号: 88504-24-9
• 分子量: 710.81
• MDL番号: MFCD11041152
• UNSPSCコード: 51171641
• PubChem Substance ID: 329823909
• NACRES: NA.22

特性

• アッセイ: >90%
• フォーム: solid or viscous liquid
• 反応適合性: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive; reagent type: linker; reactivity: thiol reactive
• ポリマー構造: shape: linear; functionality: monofunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O
• InChI: 1S/C32H58N2O15/c1-38-8-9-40-12-13-42-16-17-44-20-21-46-24-25-48-28-29-49-27-26-47-23-22-45-19-18-43-15-14-41-11-10-39-7-5-33-30(35)4-6-34-31(36)2-3-32(34)37/h2-3H,4-29H2,1H3,(H,33,35)
• InChI Key: OVCDVKBUIQUWMR-UHFFFAOYSA-N

詳細

特徴および利点

The m-dPEG^®₁₂-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₁₂-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable