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フォーム
solid
光学活性
[α]/D +69.5°, c = 0.4 in H2O(lit.)
反応適合性
reaction type: solution phase peptide synthesis
色
off-white
溶解性
H2O: soluble
アプリケーション
peptide synthesis
SMILES記法
[H][C@]1(C[C@@H]1C(O)=O)[C@H](N)C(O)=O
InChI
1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1
InChI Key
GZOVEPYOCJWRFC-UZBSEBFBSA-N
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生物化学的／生理学的作用
Potent NMDA receptor agonist.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
最新バージョンのいずれかを選択してください：
Cynthia Levinthal et al.
Pharmacology, 83(2), 88-94 (2008-12-10)
Protons act as neuromodulators and produce significant effects on synaptic transmission. The molecular basis of neuromodulation by extracellular protons is partially explained by their effects on certain neurotransmitter receptors and ion channels. The metabotropic glutamate receptors (mGluRs) are a family
Maria Smiałowska et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 32(6), 1242-1250 (2006-11-30)
Earlier studies conducted by our group and by other authors indicated that metabotropic glutamatergic receptor (mGluR) ligands might have anxiolytic activity and that amygdalar neuropeptide Y (NPY) neurons were engaged in that effect. Apart from the amygdala, the hippocampus, another
Timo Kirschstein et al.
Neuropharmacology, 47(2), 157-162 (2004-06-30)
Specific agonists of metabotropic glutamate receptors (mGluRs) provide powerful tools to discriminate afferent fibers originating from different presynaptic neurons. The group II mGluR agonists L-CCG-I ((2S,1'S,2'S)-2-(2-carboxycyclopropyl)glycine) and DCG-IV ((2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine) are commonly used to distinguish between mossy fiber and associational-commissural (A/C)
Ke-Zhong Shen et al.
The Journal of physiology, 553(Pt 2), 489-496 (2003-09-23)
Patch pipettes were used to record currents in whole-cell configuration to study the effects of group II metabotropic glutamate receptor (mGluR) stimulation on synaptic transmission in slices of rat subthalamic nucleus. Evoked glutamatergic excitatory postsynaptic currents (EPSCs) were reversibly reduced
Pradeep Kumar et al.
Organic & biomolecular chemistry, 10(34), 6987-6994 (2012-07-27)
An efficient high yielding improved method for the enantio- and diastereoselective cyclopropanation of chiral epoxides using triethylphosphonoacetate and base (Wadsworth-Emmons cyclopropanation) is reported. The utility of this protocol is illustrated by concise and practical synthesis of cascarillic acid, grenadamide and
資料
Our new product range of pharmaceutical impurity solutions as certified reference materials (CRMs) save costs and labor by providing all impurities listed in the USP as well as in the EP in one mix.
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