933724

Linear polyethylenimine-block-poly(ethylene glycol)

PEG average M_n 5,000, PEI average M_n 10,000

• 別名: PEG-PEI, PEG-b-PEI, Poly(ethylene glycol)-block-polyethylenimine
• 化学式: CH₃(C₂H₄O)_n(C₂H₅N)_mOH
• UNSPSCコード: 12352207
• NACRES: NA.21

特性

• 形状: powder or solid
• 品質水準: 100
• 分子量: PEG M_n 5,000 Da; PEG average M_n 5,000; PEI M_n 10,000 Da; PEI average M_n 10,000
• 色: white to pale yellow
• 保管温度: 2-8°C

詳細

アプリケーション

Due to their low immunogenicity profiles, polymeric nonviral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable