530301

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride

97%

• 別名: 2-(Chloromethyl)-3,4-dimethoxypyridinium hydrochloride
• 実験式（ヒル表記法）: C₈H₁₁Cl₂NO₂
• CAS番号: 72830-09-2
• 分子量: 224.08
• Beilstein: 5360726
• EC Number: 416-440-5
• MDL番号: MFCD02181083
• UNSPSCコード: 12352100
• PubChem Substance ID: 24877740
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 97%
• mp: 155 °C (dec.) (lit.)
• 官能基: chloro
• SMILES記法: Cl[H].COc1ccnc(CCl)c1OC
• InChI: 1S/C8H10ClNO2.ClH/c1-11-7-3-4-10-6(5-9)8(7)12-2;/h3-4H,5H2,1-2H3;1H
• InChI Key: YYRIKJFWBIEEDH-UHFFFAOYSA-N

詳細

詳細

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) can be synthesized using maltol as a starting material. CDP and DMS (dimethyl sulfate) are used in the preparation of pantoprazole sodium (PPS), an antiulcerative drug. The quantification of CDP and DMS in PPS can be done simultaneously by gas chromatography–mass spectrometry (GC-MS) method.

アプリケーション

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride may be used as a precursor for the preparation [(2-pyridyl)-2-ethyl]-[3,4-dimethoxy-(2-pyridylmethyl)]-N-methylamine.

安全性情報

• ピクトグラム: GHS08,GHS05,GHS07,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302 + H312,H315,H317,H318,H373,H411
• 注意書き: P273 - P280 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves