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品質水準
アッセイ
99%
フォーム
solid
mp
176-178 °C (lit.)
溶解性
water: soluble 70 mg/mL at 20 °C
官能基
amine
SMILES記法
Cc1ccccc1NC(=N)Nc2ccccc2C
InChI
1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
InChI Key
OPNUROKCUBTKLF-UHFFFAOYSA-N
遺伝子情報
human ... EBP(10682)
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詳細
1,3-Di-o-tolylguanidine is a selective σ-receptor agonist. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice.
適用法令
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Jan Code
207713-500G:
207713-100G:
207713-BULK:
207713-5G:
207713-VAR:
S A Mousavi et al.
Ultrasonics sonochemistry, 46, 26-35 (2018-05-10)
A nanostructured cationic zinc nitrate complex with a formula of [ZnLNO3]NO3 (where L = (N2E,N2'E)-N1,N1'-(ethane-1,2-diyl)bis(N2-((E)-3-phenylallylidene)ethane-1,2-diamine)) was prepared by sonochemical process and characterized by single crystal X-ray crystallography, scanning electron microscopy (SEM), FT-IR and NMR spectroscopy and X-ray powder diffraction (XRPD). The X-ray
Tomokazu Yoshinaga et al.
Antiviral research, 152, 1-9 (2018-02-08)
Cabotegravir (CAB, S/GSK1265744) is an investigational second-generation integrase strand transfer inhibitor (INSTI) with a chemical structure similar to dolutegravir. CAB is under development as a long-acting injectable formulation for treatment of HIV-1 infection and for pre-exposure prophylaxis. We conducted an
Martina Kovarova et al.
Nature communications, 9(1), 4156-4156 (2018-10-10)
Non-adherence to medication is an important health care problem, especially in the treatment of chronic conditions. Injectable long-acting (LA) formulations of antiretrovirals (ARVs) represent a viable alternative to improve adherence to HIV/AIDS treatment and prevention. However, the LA-ARV formulations currently
Takato Hiranita et al.
Behavioural pharmacology, 22(5-6), 525-530 (2011-08-03)
Previous studies demonstrated the effectiveness of selective σ-receptor (σR) agonists [1,3-di-o-tolylguanidine (DTG), PRE-084] as reinforcers in rats trained to self-administer cocaine. Similar to cocaine, these drugs increased nucleus accumbens shell dopamine levels, and effects of DTG, but not PRE-084, on
Jiping Liu et al.
Polymers, 11(5) (2019-05-16)
Modified nano-TiO2 was prepared by using triethanolamine and tetraisopropyl di (dioctylphosphate) titanate, respectively. Then the poly(p-phenylene benzobisoxazole) (PBO) fibers doped with different additions of modified nano-TiO2 particles were prepared by preparing PBO polymer solution and dry-jet wet spinning technique. Thermogravimetric
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