コンテンツへスキップ
Merck

TNNT1

troponin T type 1 (skeletal, slow)

別名:
ANM, NEM5, STNT, TNT, TNTS
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7138) Summary: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21955) troponin T1, skeletal, slow
  • Rat(171409) troponin T type 1 (skeletal, slow)
  • Zebrafish(353248) troponin T1, skeletal, slow
  • domestic cat(101086360) troponin T type 1 (skeletal, slow)
  • dog(476383) troponin T type 1 (skeletal, slow)
  • cow(282095) troponin T type 1 (skeletal, slow)
  • sheep(101122212) troponin T type 1 (skeletal, slow)
  • domestic guinea pig(100720501) troponin T type 1 (skeletal, slow)
  • naked mole-rat(101713798) troponin T type 1 (skeletal, slow)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

製品番号
詳細
Species
Human TNNT1 / Troponin T, Slow Skeletal Muscle ELISA Kit, ,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Troponin T antibody, Mouse monoclonal, clone JLT-12, purified from hybridoma cell culture,
交差性
bovine, goat, human, mouse, rabbit, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗TNNT1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗TNNT1 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human, mouse
アプリケーション
western blot
Anti-TNNT1 antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rat
アプリケーション
western blot
モノクロナール抗トロポニンT マウス宿主抗体, clone JLT-12, ascites fluid,
交差性
bovine, chicken, rabbit, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TNNT1,
Species
human
MISSION® esiRNA, targeting mouse Tnnt1,
Species
mouse